目前一些干预肠道菌群的手段比如粪菌移植（FMT）已经在包括肥胖和、艰难梭菌感染、炎症性肠病、等疾病中显示出疗效[6]，并正在/已经进入临床。

相信随着我们对肠道菌群认识的不断深入，肠道会成为我们预防或治疗常见的人类疾病的新的有效途径。

参考文献：

1.Sender R, Fuchs S, Milo R. Revised Estimates for the Number of Human and Bacteria Cells in the Body. PLoS Biol. 2016;14(8):e1002533. Published 2016 Aug 19. doi:10.1371/journal.pbio.1002533

2.Gomes AC, Hoffmann C, Mota JF. The human gut microbiota: Metabolism and perspective in obesity.Gut Microbes. 2018;9(4):308-325. doi:10.1080/19490976.2018.1465157

3.Palmas V, Pisanu S, Madau V, et al. Gut microbiota markers associated with obesity and overweight in Italian adults.Sci Rep. 2021;11(1):5532. Published 2021 Mar 9. doi:10.1038/s41598-021-84928-w

4.Qin J, Li Y, Cai Z, et al. A metagenome-wide association study of gut microbiota in type 2 diabetes.Nature. 2012;490(7418):55-60. doi:10.1038/nature11450

5.Oteng AB, Kersten S. Mechanisms of Action of trans Fatty Acids.Adv Nutr. 2020;11(3):697-708. doi:10.1093/advances/nmz125

6.Ooijevaar RE, Terveer EM, Verspaget HW, Kuijper EJ, Keller JJ. Clinical Application and Potential of Fecal Microbiota Transplantation.Annu Rev Med. 2019;70:335-351. doi:10.1146/annurev-med-111717-122956